Vascular endothelial growth factor gene polymorphisms in North Indian patients with recurrent miscarriages

This reproductive genetics study evaluated VEGF polymorphisms in North Indian women with recurrent miscarriages to determine whether altered angiogenic signaling contributes to pregnancy loss. The analysis linked specific VEGF variants to miscarriage susceptibility, supporting the concept that impaired uteroplacental vascular regulation is part of the disease mechanism. These findings connected angiogenic genetics with the broader immunologic and vascular framework of recurrent pregnancy loss.